Karine is renowned Anishinaabe-Métis historian. She served as Director of Research for the National Inquiry into Missing and Murdered Indigenous Women and Girls, drafting the Final Report and managing its Forensic Document Review Project and Legacy Archive. She was formerly an Adjunct Professor at the University of Winnipeg and Director of Research for Jerch Law Corporation. From 2016 to 2018, she also served as Curator at the Canadian Museum for Human Rights.